[et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Header section” _builder_version=”3.22.3″ custom_padding=”0px|0px|0|0px|false|false”][et_pb_fullwidth_header title=”HIRREM” text_orientation=”center” background_overlay_color=”rgba(0,0,0,0)” content_max_width_last_edited=”off|desktop” admin_label=”hero image” _builder_version=”4.2.2″ title_font=”Oswald|||on|||||” title_text_align=”center” title_text_color=”#ffffff” title_font_size=”50px” subhead_font=”Nunito|600|||||||” subhead_font_size=”20px” subhead_line_height=”1.9em” background_color=”rgba(255,255,255,0)” background_image=”https://cereset.com/wp-content/uploads/2019/12/brain-and-behavior-cover-hero.jpg” custom_button_one=”on” button_one_text_size=”15px” button_one_bg_color=”#dca57d” button_one_border_width=”10px” button_one_border_color=”#dca57d” button_one_border_radius=”0px” button_one_letter_spacing=”3px” button_one_font=”Oswald|||on|” button_one_use_icon=”off” width=”100%” max_width=”100%” module_alignment=”center” custom_margin=”0px|0px|0px|0px|true|true” custom_padding=”0px|0px|0px|0px|true|true” animation_style=”fade” animation_starting_opacity=”50%” animation_speed_curve=”ease-in” hover_enabled=”0″ title_font_size_tablet=”” title_font_size_phone=”40px” title_font_size_last_edited=”on|desktop” custom_css_title=”display: flex;||align-items: flex-start;||justify-content: center;||position:relative; top: 10px;||padding: 0;||min-height: 50vh;||height: 50vh;” button_one_text_size__hover_enabled=”off” button_one_text_size__hover=”null” button_two_text_size__hover_enabled=”off” button_two_text_size__hover=”null” button_one_text_color__hover_enabled=”off” button_one_text_color__hover=”null” button_two_text_color__hover_enabled=”off” button_two_text_color__hover=”null” button_one_border_width__hover_enabled=”off” button_one_border_width__hover=”null” button_two_border_width__hover_enabled=”off” button_two_border_width__hover=”null” button_one_border_color__hover_enabled=”on” button_one_border_color__hover=”#c99872″ button_two_border_color__hover_enabled=”off” button_two_border_color__hover=”null” button_one_border_radius__hover_enabled=”on” button_one_border_radius__hover=”0px” button_two_border_radius__hover_enabled=”off” button_two_border_radius__hover=”null” button_one_letter_spacing__hover_enabled=”on” button_one_letter_spacing__hover=”3px” button_two_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover=”null” button_one_bg_color__hover_enabled=”on” button_one_bg_color__hover=”#c99872″ button_two_bg_color__hover_enabled=”off” button_two_bg_color__hover=”null”][/et_pb_fullwidth_header][/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.3″ custom_padding=”||0px|||”][et_pb_row _builder_version=”4.0.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”||||false|false” custom_padding=”||0px|||”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”Research Into” _builder_version=”4.0.6″ custom_padding=”||2px|||”]
HIRREM ®
HIRREM, or High-resolution, Relational, Resonance-based Electroencephalic Mirroring®, peer-reviewed papers have been published in Brain and Behavior, Journal of Neuroimaging, Frontiers in Public Health, Frontiers in Psychology, Military Medical Research, Experimental Brain Research, BMC Psychiatry, Sports Medicine Open, and The Journal of the North American Menopause Society.
HIRREM is evolving into Cereset® Research; for more detailed information on HIRREM, including a list of abstracts and presentations, please visit our Cereset Research page here.
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Peer-reviewed Scientific Publication Reference
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Lee SW, Laurienti PJ, Burdette JH, Tegeler CL, Morgan AR, Simpson SL, Gerdes L, Tegeler CH (2018). Functional Brain Network Changes Following Use of an Allostatic, Closed‐Loop, Acoustic Stimulation Neurotechnology for Military‐Related Traumatic Stress. J. Neuroimaging. 10 October 2018. https://onlinelibrary.wiley.com/doi/10.1111/jon.12571
Shaltout HA, Lee SW, Tegeler CL, Hirsch JR, Simpson SL, Gerdes L, and Tegeler CH. (2018). Improvements in Heart Rate Variability, Baroreflex Sensitivity, and Sleep After Use of Closed-Loop Allostatic Neurotechnology by a Heterogeneous Cohort. Front. Public Health. 25 April 2018. 10:3389. https://www.frontiersin.org/articles/10.3389/fpubh.2018.00116/full
Tegeler CL, Gerdes L, Shaltout HA, Cook JF, Simpson SL, Lee SW and Tegeler CH. (2017). Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self- reported and autonomic improvements. Military Medical Research. 22 December 2017. https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-017-0147-0
Tegeler CH, Cook JF, Tegeler CL, Hirsch JR, Shaltout HA, Simpson SL, Fidali B, Gerdes L, and Lee SW. (2017). Clinical, hemispheric, and autonomic changes associated with use of closed-loop, allostatic neurotechnology by a case series of individuals with self-reported symptoms of post-traumatic stress. BMC Psychiatry. 19 April 2017. https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-017-1299-x
Tegeler CH, Tegeler CL, Cook JF, Lee SW, Gerdes L, Shaltout HA, Miles CM, and Simpson SL. (2016). A preliminary study of the effectiveness of an allostatic, closed-loop, acoustic stimulation neurotechnology in the treatment of athletes with persisting post-concussion symptoms. Sports Medicine – Open. 14 September 2016. https://sportsmedicine-open.springeropen.com/articles/10.1186/s40798-016-0063-y
Fortunato JE, Tegeler CL, Gerdes L, Lee SW, Pajewski NM, Franco ME, Cook JF, Shaltout HA, Tegeler CH. (2016). Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome is associated with improvements in heart rate variability and changes in temporal lobe electrical activity. Experimental Brain Research.
Tegeler CH, Shaltout HA, Tegeler CL, Gerdes L, and Lee SW. (2015). Rightward dominance in temporal high-frequency electrical asymmetry corresponds to higher resting heart rate and lower baroreflex sensitivity in a heterogeneous population. Brain Behav. 01 May 2015. https://onlinelibrary.wiley.com/doi/10.1002/brb3.343
Tegeler CH, Tegeler CL, Cook JF, Lee SW, and Pajewski NM. (2015). Reduction in menopause-related symptoms associated with use of a noninvasive neurotechnology for autocalibration of neural oscillations. Menopause. June 2015. https://journals.lww.com/menopausejournal/Pages/articleviewer.aspx?year=2015&issue=06000&article=00011&type=Fulltext
Lee SW, Gerdes L, Tegeler CL, Shaltout HA, and Tegeler CH. (2014). A bihemispheric autonomic model for traumatic stress effects on health and behavior. Front. Psychol. 5:843. http://journal.frontiersin.org/article/10.3389/fpsyg.2014.00843/full
Gerdes L, Gerdes P, Lee SW, and Tegeler CH. (2013). HIRREM: a non-invasive, allostatic methodology for relaxation and auto-calibration of neural oscillations. Brain Behav. Mar; 3(2): 193-205. https://onlinelibrary.wiley.com/doi/10.1002/brb3.116
Tegeler CH, Kumar S, Conklin D, Lee SW, Gerdes EL, Turner DP, Tegeler CL, Fidali B, and Houle TT. (2012). Open label, randomized, crossover pilot trial of high resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) to relieve insomnia. Brain Behav. 28 October 2012. https://onlinelibrary.wiley.com/doi/10.1002/brb3.101
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CURRENT CLINICAL STUDIES
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Military Neurotechnology Following Traumatic Brain Injury (Cereset) Study : A randomized research trial for individuals with persisting symptoms following mild-Traumatic Brain Injury (mTBI). The research trial is being conducted in two locations–Uniformed Services University of the Health Sciences (USUHS) in Bethesda, MD; and Womack Army Medical Center (WAMC) in Fort Bragg, NC (NCT03649958) INTERIM RESULTS PRESS RELEASE (PRWEB)
Military PTSD Study : An open label pilot trial to evaluate the use of HIRREM as an adjunct for service members or Veterans with military-related symptoms of traumatic stress (NCT03230890)
Primary Hypertension Study : A randomized clinical trial for patients with Primary Hypertension (high blood pressure with no clearly identified cause), who have blood pressures between 130-159 mmHg systolic, and 80-99 mmHg diastolic. This study compares the use of in-office HIRREM plus continued current care to continued current care alone (NCT03479697)
Hot Flashes Study : A randomized clinical trial for women with menopause-related hot flashes, comparing the use of in-office HIRREM plus continued current care to continued current care alone (NCT03512002)
Insomnia Study : A randomized, controlled clinical trial for those with insomnia. This study evaluates the use of HIRREM-SOP, an updated approach based on the same HIRREM core technology previously utilized, using new hardware and software, and a standardized series of protocols. The study compares a series of in-office HIRREM-SOP sessions (acoustic stimulation linked to brainwaves), to acoustic stimulation not linked to brainwaves (NCT03607994).
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PENDING CLINICAL STUDIES
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